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GHRP-6 (5 mg) – Potent Growth Hormone-Releasing Peptide
1. Compound Profile
GHRP-6 (Growth Hormone-Releasing Peptide-6) is a first-generation synthetic hexapeptide that powerfully stimulates pituitary GH secretion through ghrelin receptor activation. It is particularly noted for its strong appetite-stimulating effects, making it valuable for both muscle growth research and studies on cachexia/wasting disorders.
2. Scientific Mechanism
Binds to GHS-R1a receptors, triggering dose-dependent GH release
Markedly increases hunger (strongest appetite stimulation among GHRPs)
Elevates IGF-1 levels for enhanced anabolic activity
Modestly increases prolactin and cortisol (more pronounced than GHRP-2)
3. Research Applications
Muscle Protein Synthesis: Promotes nitrogen retention & hypertrophy
Metabolic Enhancement: Supports fat oxidation & nutrient partitioning
Wasting Conditions: May counteract muscle atrophy in catabolic states
Gut Motility: Shows potential gastroprotective effects in studies
4. Administration Protocol
Dosage Range: 100-300 mcg, 2-3x daily (fasted state preferred)
Optimal Timing: Pre-meal (for appetite effects) or pre-workout
Cycle Duration: 6-8 weeks (to prevent receptor desensitization)
Delivery Method: Subcutaneous injection (most common)
5. Observed Side Effects
Significant hunger stimulation (may be undesirable for some research models)
Mild water retention (typically transient)
Possible joint discomfort at higher doses
Temporary flushing/tingling post-injection
6. Synergistic Combinations
With CJC-1295: Creates powerful GH/IGF-1 amplification
With Mod GRF 1-29: For more physiological GH pulses
With MK-677: Alternative for oral GH secretagogue studies
7. Product Specifications
Purity: ≥98% (HPLC-verified)
Molecular Weight: 873.0 g/mol
Form: Lyophilized white powder (5 mg/vial)
Storage: 2-8°C (stable for 2 years lyophilized, 1 week reconstituted)
Important Notice:
This product is intended solely for laboratory research purposes under controlled conditions. Not for human consumption, diagnostic use, or veterinary applications. Researchers must comply with all applicable regulations governing peptide studies in their jurisdiction.
